Reply to Laura Fisher, M.D.

Dear Dr.         Have you tried the coconut oil Dr. Mary Newport has described as a miracle treatment for her husband? Do you take fish oil (three or more caps per day)? Do you take testosterone replacement (skin gel)? Do you take selegiline or rasagiline? What if any vitamins and other supplements do you take? It is not completely clear to me how you were diagnosed. Was it based on an MRI coupled with some behavioral and subjective changes?
My father died in his eighties of combined LBD and Alzheimer’s disease and I am trying not to follow his example.
Sincerely,
Laura Fisher

Hi Dr. Fisher……………No, I have not tried the coconut oil. I need to study more about it. I am on Aricept 10-mg daily, Namenda 10-mg twice daily, 9 capsules of double strength fish oil, testosterone replacement therapy along with trazodone (for sleep). I take multivitamins, calcium and magnesium supplements along with vitamin D and B-complex daily. When I think about it, I take a vitamin E capsule as well. I’ve not gone overboard with all that’s recommended out there. Ah, yes. I do like my coffee in the morning and the good old home made iced tea!

I am now on a steady plateau with the above combination and am permitted to drive as long as I have a co-pilot with me. I’ve noticed the biggest difference since adding the Namenda to my regimen. I do find I slip backwards if I don’t use the testosterone replacement therapy. I’d love to be able to practice medicine again but have not totally come back to my base level. I still have enough deficits to keep me from totally functioning normally. I do well with regular activities of daily living as long as there is little pressure. Hobbies, crafts, gardening, TV, etc. Short term memory and immediate recall are still some problems for me as well as word finding difficulties.

I was diagnosed at the University of California, San Francisco’s Memory Clinic after being hospitalized for the entire evaluation. I following an LBD expert neurologist in Pittsburgh, PA. Pet scans of the brain have also shown the pathological changes as well.

I’ve never specifically been treated for my Parkinsonian symptoms. Azilect would certainly be something to discuss with my neurologist. During my last visit, he did mention starting an anti-Parkinsonian agent but I would like to hold off on that as long as possible.

Hope this helps……

Warmly………….David

Thursday afternoon October 23, 2008

Please pass the salmon (omega 3 fatty acids). I’ll skip the omega 6s and 9s, thank you very much.

 

Well, I did this logic puzzle yesterday. I started by printing it out and using a pencil. The eraser wore then so I resorted to doing it online….much easier to just click in the dots and Xs. Wow! I really felt an uplifting after doing it. Great fun!!

 

— A note to God today…….thank you for food, for the health I have (no tremors today, I have energy, raked leaves and went food shopping with Pam), for friends, for the money you’ve provided and for freedom. Please remember the folks who are hungry, sick, poor, friendless and those who are not free. Help me to share and to serve other people in the best way I can today. Thank you, God. — Oh yea, God. I think this prayer kinda comes from something I learned as a kid. I think it might be a scripture verse in the Bible. If it is, forgive me, because I don’t read the Bible all the time.

 

Now to the omega fatty acids — 3 and 6. Don’t even bother with the 9s and don’t waste your money on supplements that have the 6 and 9 in them! First I suggest reading this introductory article. 

Omega-3 fatty acids can be found in less foods than omega-6 fatty acids. Many people have a very low intake of omega-3s. Since omega-6 fatty acids compete with omega-3 fatty acids for use in the body, it is important to take these fatty acids in the proper ratio. The ratio of omega-6 to omega-3 should be about 2:1. Since most diets are very rich in omega-6 and low in omega-3, the ratio is often somewhere between 10:1 and 30:1. This is especially a problem with diets that are high in processed foods and oils. OIls like corn, safflower, sunflower and cottonseed are usually low in omega-3s. To balance the fatty acids out, it is important to eat a diet that is low in processed foods and with fat mainly coming from omega-3 fatty acids.

Flaxseed vs Fish oil

 

First, the type of omega 3’s vary in each. In flax seed oil, the omega 3’s come in the form of ALA. In fish oils, they come in the form of DHA and EPA. ALA needs to be converted by the body into DHA and EPA. This conversion does not always happen easily or smoothly for people, particularly those people with less than optimal health….which often includes elderly folk.

 

For this reason, many (including us here) argue that high quality fish oils are are a better source of omega 3’s than flax seed oil because you are getting DHA and EPA directly without need for conversion. Flaxseed oil and flaxseed remain wonderful nutritional agents for their own reasons. But they will not substitute for fish oil in your program. Only fish oil–the real thing–does the job.

 

A high omega-6/omega-3 ratio, as is found in today’s Western diets, promotes the pathogenesis of many chronic diseases, including cardiovascular disease. Omega-3 fatty acids have strong anti-inflammatory effects whereas omega-6 fatty acids tend to lead to inflammation. Because inflammation is at the base of many chronic diseases, including coronary heart disease, dietary intake of omega-3 fatty acids plays an important role in the manifestation of disease.

 

Click here for a list of foods with omega 3 and 6s along with the ratios.

 

And click here for a great explanation of how omega fatty acids work. Greg Cole, professor of medicine and neurology at the David Geffen School of Medicine at UCLA and associate director of UCLA’s Alzheimer Disease Research Center, and his colleagues report that the omega-3 fatty acid docosahexaenoic acid (DHA) found in fish oil increases the production of LR11, a protein that is found at reduced levels in Alzheimer’s patients and which is known to destroy the protein that forms the “plaques” associated with the disease.

 

The plaques are deposits of a protein called beta amyloid that is thought to be toxic to neurons in the brain, leading to Alzheimer’s. Since having high levels of LR11 prevents the toxic plaques from being made, low levels in patients are believed to be a factor in causing the disease.
David

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